Halten av miljöföroreningen PFOS i blod - Arbets- och

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5. achieve a specific function must be stated, but has no impact on the assessment. ☐ Yes. ☐ No PFOS (perfluorooctanesulfonates). Potentially FIND function under the EDIT tab, enter the full or partial product Role of A. Schulman under REACH PFOS (perfluorooctanesulfonates). av V Franke · Citerat av 3 — for aqueous perfluorooctanesulfonate (PFOS) and perfluorooctanoate.

Perfluorooctanesulfonate function

PFOS, perfluorohexanesulfonate (PFHxS), perfluorooctanoate (PFOA), and perfluorooctanesulfonamide (PFOSA) have been found in human sera from the United States. Ulla Nordström Joensen, Bruno Veyrand, Jean-Philippe Antignac, Martin Blomberg Jensen, Jørgen Holm Petersen, Philippe Marchand, Niels Erik Skakkebæk, Anna-Maria Andersson, Bruno Le Bizec, Niels Jørgensen, PFOS (perfluorooctanesulfonate) in serum is negatively associated with testosterone levels, but not with semen quality, in healthy men, Human Reproduction, Volume 28, Issue 3, March 2013 2020-10-01 · PFOS potentially dysregulates lipids that play important roles in immune functions. Abstract Perfluorooctanesulfonate (PFOS) is a man-made chemical widely used in industrial products. Corrigendum to "Renal function and isomers of perfluorooctanoate (PFOA) and perfluorooctanesulfonate (PFOS): Isomers of C8 health project in China" [Chemosphere 218 (2019) 1042-1049] Chemosphere . 2019 Apr;220:1208. doi: 10.1016/j.chemosphere.2019.01.051.

This work presents, for the first time, a synergistic approach for the targeted affinity-based capture of PFOS using a porous sorbent probe Perfluorooctanesulfonate (PFOS) Perturbs Male Rat Sertoli Cell Blood-Testis Barrier Function by Affecting F-Actin Organization via p-FAK-Tyr(407): An in Vitro Study Perfluorooctanesulfonate (PFOS, heptadecafluorooctanesulfonic acid, potassium salt, Mr 538.22) was purchased from Sigma-Aldrich (St. Louis, MO) and dissolved in DMSO at 100 mM so that when the Sertoli cells were treated with 20μM PFOS, the concentration of DMSO in … Perfluorooctanoic acid (PFOA) and perfluorooctanesulfonate (PFOS) are man-made compounds with widespread presence in human sera. In previous occupational and adult studies, PFOA and PFOS were Erratum: Perfluorooctanesulfonate (PFOS)-induced Sertoli cell injury In the Results section, under the sub-heading ‘PFOS perturbs Sertoli cell TJ-barrier function through changes in HP10 Toxic for reproduction: waste which has adverse effects on sexual function and fertility in adult males and females, as well as developmental toxicity in the offspring.

Publications – Page 73 – Department of Environmental Science

sulfonate, perfluorooctanoic acid, and perfluorooctane sulfonate. Alternative methods to safety studies in experimental animals: role in the Perfluorooctane sulfonate exposure causes gonadal developmental av Y Lind — Carpene E, Andream G, Isam G (2007) Metallothionein functions and structural Yu W-G, Liu W, Jin Y-H (2009) Effects of perfluorooctane sulfonate on rat with perfluorooctane sulfonate (PFOS) as the predominant compound.

Effects of pH and cation composition on sorption of per-and

Joensen UN, Veyrand B, Antignac JP, Blomberg Jensen M, Petersen JH, Marchand P, Skakkebæk NE, Andersson AM, Le Bizec B, Jørgensen N Hum Reprod 2013 Mar;28(3):599-608. Figure S3: The mass spectra of two peptides by MALDI-TOF. Figure S4: The maximal fluorescence emission plot (measured at 470 nm) for 1,8-ANS in the presence of peptides as a function of 1,8-ANS concentration and relative fluorescence intensity of 1,8-ANS as a function of added PFOS or 6:2 Cl-PFESA concentrations. Perfluorooctanesulfonate or perfluorooctanesulfonic acid (PFOS) and its related products such as perfluorooctanoate (PFOA) were first produced by 3M in 1949 as fluorosurfactants, serving as a fabric protector (such as a key ingredient in Scotchgard) and an active component in stain repellents by lowering surface tension of water. Potassium perfluorooctanesulfonate | C8F17KO3S | CID 23669238 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. Perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) are among the most prominent contaminants in human serum, and these were historically manufactured as technical mixtures of linear and branched isomers.

The Toxicologist 66(1): 25 (Abstract 120), 2002. Perfluorooctanesulfonate (PFOS) Perturbs Male Rat Sertoli Cell Blood-Testis Barrier Function by Affecting F-Actin Organization via p-FAK-Tyr 407: An in Vitro Study Hin-Ting Wan , Hin-Ting Wan Perfluorooctanesulfonic acid (PFOS) (conjugate base perfluorooctanesulfonate) is an anthropogenic fluorosurfactant and global pollutant. PFOS was the key ingredient in Scotchgard, a fabric protector made by 3M, and numerous stain repellents.
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Environmental toxicants such as perfluorooctanesulfonate (PFOS) have been implicated in male reproductive dysfunction, including reduced sperm count and semen quality in humans.

Joensen UN, Veyrand B, Antignac JP, Blomberg Jensen M, Petersen JH, Marchand P, Skakkebæk NE, Andersson AM, Le Bizec B, Jørgensen N … Environmental toxicants such as perfluorooctanesulfonate (PFOS) have been implicated in male reproductive dysfunction, including reduced sperm count and semen quality, in humans. However, the underlying mechanism(s) remains unknown. Herein PFOS … Environmental toxicants such as perfluorooctanesulfonate (PFOS) have been implicated in male reproductive dysfunction, including reduced sperm count and semen quality in humans.
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SERUM LIPIDS - Uppsatser.se

doi: 10.1016/j.chemosphere.2019.01.051. Perfluorooctanesulfonate [PFOS; CF 3 (CF 2) 7 SO 3 −] and its acid salts were derived from perfluorooctanesulfonyl fluoride [POSF; CF 3 (CF 2) 7 SO 2 F]. Major product applications were developed using POSF through formation of N-alkylsulfonamides that were used in surfactants, paper and packaging treatments, and surface protectants (e.g., carpet, upholstery, textiles).

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Screening of PFASs in groundwater and surface water - SLU

However, the underlying mechanism(s) remains unknown. PFOS (perfluorooctanesulfonate, or perfluorooctane sulfonic acid) These findings thus illustrate PFOS exerts its disruptive effects on Sertoli cell function downstream through Akt1/2. AB - Introduction: Perfluorooctanesulfonate (PFOS) is widely distributed and persistent in humans and wildlife. Prior toxicological studies have reported decreased total and free thyroid hormones in serum without a major compensatory rise in thyrotropin (TSH) or altered thyroid gland histology. 2020-10-01 · PFOS potentially dysregulates lipids that play important roles in immune functions.

Grundvattenmodellering och föroreningstransport av PFOS i

Figure S4: The maximal fluorescence emission plot (measured at 470 nm) for 1,8-ANS in the presence of peptides as a function of 1,8-ANS concentration and relative fluorescence intensity of 1,8-ANS as a function of added PFOS or 6:2 Cl-PFESA concentrations. Perfluorooctanesulfonate or perfluorooctanesulfonic acid (PFOS) and its related products such as perfluorooctanoate (PFOA) were first produced by 3M in 1949 as fluorosurfactants, serving as a fabric protector (such as a key ingredient in Scotchgard) and an active component in stain repellents by lowering surface tension of water. Potassium perfluorooctanesulfonate | C8F17KO3S | CID 23669238 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. Perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) are among the most prominent contaminants in human serum, and these were historically manufactured as technical mixtures of linear and branched isomers. Perfluorooctanesulfonate (PFOS) is an environmental toxicant used in developing countries, including China, as a stain repellent for clothing, carpets and draperies, but it has been banned in the PFOS levels were negatively associated with testosterone (T), calculated free testosterone (FT), free androgen index (FAI) and ratios of T/LH, FAI/LH and FT/LH. Other PFCs were found at lower levels than PFOS and did not exhibit the same associations. PFC levels were not significantly associated with semen quality.

Corrigendum to “Renal function and isomers of perfluorooctanoate (PFOA) and perfluorooctanesulfonate (PFOS): Isomers of C8 health project in China” (Chemosphere (2019) 218 (1042–1049), (S0045653518322987) (10.1016/j.chemosphere.2018.11.191)) Serum concentrations of perfluorooctanesulfonate and other fluorochemicals in an elderly population from Seattle, Washington T seng, C., et al: Analysis of perfluorooctanesulfonate and related fluorochemicals in water and biological tissue samples by liquid chromatography-ion trap mass spectrometry, J. Chromatogr. A, 1105 (2006), pp. 119-126 [5] PFOS (perfluorooctanesulfonate, or perfluorooctane sulfonic acid) is an anthropogenic fluorosurfactant widely used in consumer products.